GeneTex
United States (US)

Hypoxia

 

The development of complex anatomical and physiological systems to maintain oxygen homeostasis was an essential process in the evolution of metazoans. Hypoxia, defined as an insufficient oxygen supply to tissues, elicits a cellular response that hinges on the stabilization of hypoxia-inducible factors (HIFs). These transcription factors are subsequently able to accumulate in the nucleus and bind to DNA at “hypoxia response elements” (HREs) and subsequently drive either the expression (or, perhaps indirectly, the repression) of hundreds of genes.

Highlighted Products

      

HIF1 alpha antibody (GTX628480)

 

HIF1 beta antibody (GTX128795)

HIF2 alpha antibody (GTX632015)

 
 
 

CAIX antibody (GTX70020)

 

Heme Oxygenase 1 antibody (GTX101147)

  

PHD2 antibody (GTX132293)

 
 
 

PKM antibody (GTX107977)

  

MMP2 antibody (GTX104577)

 

VEGF antibody (GTX102643)

  
 
 

VE-cadherin antibody (GTX633705)

 

mTOR antibody (GTX101557)

 

AKT (pSer473) antibody (GTX128414)

 
 
 

PHD1 antibody (GTX123033)

 

PHD4 antibody (GTX116582)

 

VHL antibody (GTX101087)

 
 
 

PD-L1 antibody (GTX104763)

   
     

 

 

Pathways
Wnt Pathway

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature
Poster - Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Pamphlet - Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Poster - Hypoxia Regulation

Poster - Hypoxia Regulation

Download the latest version of GeneTex's hypoxia regulation poster
Literature
Flyer - Hypoxia Markers

Flyer - Hypoxia Markers

Download the latest version of GeneTex's hypoxia markers poster
Literature
Poster - Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Pamphlet - Hot Products

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Pamphlet - Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Poster - Hypoxia Regulation

Poster - Hypoxia Regulation

Download the latest version of GeneTex's hypoxia regulation poster
Literature
Flyer - Hypoxia Markers

Flyer - Hypoxia Markers

Download the latest version of GeneTex's hypoxia markers poster