Neuropeptides are small polypeptides (~3-100 residues) processed from larger precursors. Unlike conventional neurotransmitters (such as GABA, dopamine and glutamate) that are stored in small synaptic vesicles, neuropeptides are generally packaged in large dense-core vesicles that can be targeted to both axons and dendrites. They are key signaling factors involved in neuromodulation through functional interaction with neurotransmitters. Neuropeptides typically exert their effects through binding to G-protein-coupled receptors (GPCRs).
GeneTex provides a selection of neuropeptide-related products, including antibodies detecting neuropeptide precursors, mature neuropeptides, and their corresponding receptors. Please see the highlighted antibodies below.